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introduction

Yun-Long Wu

  发布时间: 2016-09-28   信息员:    浏览次数: 654

Yun-Long Wu, Ph.D

 

Professor

 

Experience

2019-now          Professor, School of Pharmaceutical Sciences, Xiamen University

2014-2019        Associate Professor, School of Pharmaceutical Sciences, Xiamen University

2012-2014        Assistant Professor, School of Pharmaceutical Sciences, Xiamen University

2010-2012        Postdoctoral Fellow, Materials Sciences and Engineering, Nanyang Technological University, Singapore

2011                       PhD, Bioengineering, National University of Singapore, Singapore

2005                       Bachelor, Materials Chemistry, University of Science and Technology of China, China

 

Research:

 

Our research interests are in the development of novel drug/gene carrier based on cyclodextrin-based nanostructure as well as injectable polymeric hydrogel or stimuli-responsive polymers for precision medicine. So far, his personal H-index is 29 and he has published more than 70 SCI papers with >2000 citations.

 

Selected Publications (*corresponding author)

 

  1. Hu, B.; Berkey, C.; Feliciano, T.; Chen, X.; Li, Z.; Chen, C.; Amini, S.; Nai, M.H.; Lei, Q.-L.; Ni, R.; Wang, J.; Leow, W.R.; Pan, S.; Li, Y.-Q.; Cai, P.; Miserez, A.; Li, S.; Lim, C.T.*; Wu, Y.-L.*; Odom, T.W.*; Dauskardt, R.H.*; Chen, X.* ²Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy.²Advanced Materials, 2020, 32(12): 1907030. (SCI impact factor: 25.809)

  2. Ke, L.; Cai, P.; Wu, Y.-L.*; Chen, X.* ²Polymeric Nonviral Gene Delivery Systems for Cancer Immunotherapy.²Advanced Therapeutics, 2020, 3(6): 1900213.

  3. Luo, Z.; Xue, K.; Zhang, X.; Lim, J. Y. C.; Lai, X.; Young, D. J.; Zhang, Z.-X.*; Wu, Y.-L.*; Loh, X. J.* ²Thermogelling Chitosan-Based Polymers for the Treatment of Oral Mucosa Ulcers.²Biomaterials Science, 2020, 8(5): 1364-1379. (SCI impact factor: 5.251)

  4. Liu, Y.; Xu, C.; Fan, X.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* ²Preparation of Mixed Micelles Carrying Folates and Stable Radicals Through PLA Stereocomplexation for Drug Delivery.²Materials Science and Engineering: C, 2020, 108: 110464. (SCI impact factor: 4.959)

  5. Luo, Z.; Jiang, L.; Yang, S.; Li, Z.*; Soh, W. M. W.; Zheng, L.*; Loh, X. J.*; Wu, Y.-L.*²Light-Induced Redox-Responsive Smart Drug Delivery System by Using Selenium-Containing Polymer@MOF Shell/Core Nanocomposite.²Advanced Healthcare Materials, 2019, 8(15): 1900406. (SCI impact factor: 6.270)

  6. Wu Y.-L.*; Li, Z* ²The Perspectives of Using Unimolecular Micelles in Nanodrug Formulation.²Therapeutic Delivery, 2019, 10(6): 333-335.

  7. Liu, X.; Li, Z.; Loh, X.; Chen, K.; Li, Z.; Wu Y.-L.*²Targeted and Sustained Co-Release of Chemotherapeutics and Gene by Injectable Supramolecular Hydrogel for Drug-Resistant Cancer Therapy.²Macromolecular Rapid Communications, 2019, 40(5): 1800117. (SCI impact factor: 4.078)

  8. Cheng, H.; Fan, X.; Wu, C.; Wang, X.; Wang, L.-J.; Loh, X.-J.*; Li, Z.*; Wu Y.-L.*²Cyclodextrin-Based Star-Like Amphiphilic Cationic Polymer as a Potential Pharmaceutical Carrier in Macrophages.²Macromolecular Rapid Communications, 2019, 40(5): 1800207. (SCI impact factor: 4.078)

  9. Luo, Z.; Xu, Y.; Ye, E.; Li, Z.*; Wu, Y.-L.*²Recent Progress in Macromolecules Anchored Gold Nanoparticle Hybrid System for Therapeutic Applications.²Macromolecular Rapid Communications, 2019, 40(5): 1800029. (SCI impact factor: 4.078)

  10. Chen, Y.-P.; Zhang, J.-L.; Zou, Y.; Wu, Y.-L.*²Recent Advances on Polymeric Beads or Hydrogels as Embolization Agents for Improved Transcatheter Arterial Chemoembolization (TACE).² Frontiers in Chemistry, 2019, 7: 408. (SCI impact factor: 3.782)

  11. Xu, C.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* ²Cyclodextrin-Based Sustained Gene Release Systems: A Supramolecular Solution towards Clinical Applications.² Materials Chemistry Frontiers, 2019, 3(2): 181-192.

  12. Luo, Z.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* ² Recent Progress in PolyhydroxyalkanoatesBased Copolymers for Biomedical Applications.² Biotechnology Journal, 2019, 14(12): 1900283. (SCI impact factor: 3.543)

  13. Chen, K.; Jiang, S.; Hong, Y.; Li, Z.*; Wu, Y.-L.*; Wu, C.* ²Cationic Polymeric Nanoformulation: Recent Advances in Material Design for CRISPR/Cas9 Gene Therapy.²Progress in Natural Science: Materials International, 2019, 29(6): 617-627. (SCI impact factor: 3.310)

  14. Xue, K.; Wang, X.; Yong, P. W.; Wu, Y.-L.*; Li, Z.*; Loh, X. J.* ²Hydrogels as Emerging Materials for Translational Biomedicine.² Advanced Therapeutics, 2019, 2(1): 1800088.

  15. Jiang, L.; Luo, Z.; Loh, X. J.*; Wu, Y.-L.*; Li, Z.*; ² PHA-Based Thermogel as a Controlled Zero-Order Chemotherapeutic Delivery System for the Effective Treatment of Melanoma.² ACS Applied Bio Materials, 2019, 2(8): 3591-3600.

  16. Li, W.; Xu, C.; Li, S.; Chen, X.; Fan, X.; Hu, Z.; Wu, Y.-L.*; Li, Z.*; ²Cyclodextrin Based Unimolecular Micelles with Targeting and Biocleavable Abilities as Chemotherapeutic Carrier to Overcome Drug Resistance.² Materials Science and Engineering: C, 2019, 105: 110047. (SCI impact factor: 4.959)

  17. Guan, G.; You, M.; Liu, X.; Wu, Y.-L.*; Ye, E.*; Li, Z.* ²Tris-Stabilized MoS2 Nanosheets with Robust Dispersibility and Facile Surface Functionalization.² Advanced Materials Interfaces, 2019, 6(12): 1900585. (SCI impact factor: 4.713)

  18. Han, L.-Y.; Wu, Y.-L.; Zhu, C.-Y.; Wu, C.-S.*; Yang, C.-R.* ² Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles.² Pharmaceutics, 2019, 11(2): 51. (SCI impact factor: 4.773)

  19. Kumar, J. N.*; Wu, Y.-L.; Loh, X. J.; Ho, N. Y.; Aik, S. X.; Pang, V. Y. ²The Effective Treatment of Multi-Drug Resistant Tumors with Self-Assembling Alginate Copolymers.² Polymer Chemistry, 2019, 10(2): 278-286. (SCI impact factor: 4.760)

  20. Lui, Y. S.; Sow, W. T.; Tan, L. P.*; Wu, Y.-L.; Lai, Y.; Li, H.* ²4D Printing and Stimuli-responsive Materials in Biomedical Applications.² Acta Biomaterialia, 2019, 92: 19-36. (SCI impact factor: 6.638)

  21. Zhu, C.; Chen, Z.; Gao, S.; Goh, B.; Samsudin, I.; Lwe, K.; Wu, Y.-L.; Wu C.; Su, X.* ²Recent Advances in Non-Toxic Quantum Dots and Their Biomedical Applications.²Progress in Natural Science: Materials International, 2019, 29(6): 628-640. (SCI impact factor: 3.310)

  22. Wang, T.;  Qi, D.;  Yang, H.; Liu, L.; Wang, M.; Leow, W. R.; Chen, G.; Yu, J.; He, K.; Cheng, H.; Wu, Y.-L.; Zhang, H.*; Chen, X.* ²Tactile Chemomechanical Transduction Based on an Elastic Microstructured Array to Enhance the Sensitivity of Portable Biosensors.² Advanced Materials, 2019, 31(1): 1803883. (SCI impact factor: 25.809)

  23. Cai, P.; Li, Z.; Keneth, E. S.; Wang, L.; Wan, C.; Jiang, Y.; Hu, B.; Wu, Y.-L.; Wang, S.; Lim, C. T.; Makeyev, E. V.; Magdassi, S.*; Chen, X.* ²Differential Homeostasis of Sessile and Pendant Epithelium Reconstituted in a 3D-Printed “GeminiChip”.² Advanced Materials, 2019, 31(28): 1900514. (SCI impact factor: 25.809)

  24. Luo, Z.; Jiang, L.; Ding, C.; Hu, B.; Loh, X. J.; Li, Z.*; Wu, Y.-L.*²Surfactant Free Delivery of Docetaxel by Poly[(R)-3-hydroxybutyrate-(R)-3-hydroxyhexanoate]-Based Polymeric Micelle for Effective Melanoma Treatments.²Advanced Healthcare Materials, 2018, 7(23): 1801221. (SCI impact factor: 5.609)

  25. Cheng, H.; Fan, X.; Wang, X.; Ye, E.; Loh, X. J.*; Li, Z.*; Wu, Y.-L.*²Hierarchically Self-Assembled Supramolecular Host-Guest Delivery System for Delivery of Chemotherapeutics to Drug Resistant Cancer Tumors.²Biomacromolecules, 2018, 19(6): 1926-1938. (SCI impact factor: 5.738)

  26. Cheng, H.; Wu, Z.; Wu, C.; Wang, X.; Liow, S. S.;Li, Z.; Wu, Y.-L.* ²Overcoming STC2 Mediated Drug Resistance Through Drug and Gene Co-delivery by PHB-PDMAEMA Cationic Polyester in Liver Cancer Cells.²Materials Science and Engineering: C, 2018, 83: 210-217. (SCI impact factor: 5.080)

  27. Chen,  X.; Chen, Z.; Hu, B.; Cai, P.; Wang, S.; Xiao, S.; Wu, Y.-L.*; Chen, X.* ²Synergistic Lysosomal Activatable Polymeric Nanoprobe Encapsulating pH Sensitive Imidazole Derivative for Tumor Diagnosis.²Small, 2018, 14(9): 1703164. [Highlighted by Materials Views China: http://www.materialsviewschina.com/2018/02/27859/] (SCI impact factor: 9.598)

  28. Fan, X.; Cheng, H.; Wang, X.; Ye, E.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* ²Thermo-responsive Supramolecular Chemotherapy by “V”-shape Armed b-Cyclodextrin Star Polymer to Overcome Drug Resistance.² Advanced Healthcare Materials, 20187(7): 1701143. (SCI impact factor: 5.609)

  29. Liu, X.; Fan, X.; Jiang, L.; Loh, X. J.; Wu, Y.-L.*; Li, Z.* ²Biodegradable Polyester Unimolecular Systems as Emerging Materials for Therapeutic Applications.² Journal of Materials Chemistry B, 2018, 6(35): 5488-5498. (SCI impact factor: 4.776)

  30. Fan, X.; Cheng, H.; Wu, Y.; Loh, X. J.*; Wu, Y.-L.*; Li, Z.* ²Incorporation of Polycaprolactone to Cyclodextrin-based Nanocarrier for Potent Gene Delivery.² Macromolecular Materials and Engineering, 2018, 303(9): 1800255. (SCI impact factor: 2.690)

  31. Chan, B.Q.Y.; Cheng, H.; Liow, S.S.; Dou, Q.; Wu, Y.-L.*; Loh, X. J.*; Li, Z.* ²Poly(carbonate urethane)-Based Thermogels with Enhanced Drug Release Efficacy for Chemotherapeutic Applications.²Polymers, 2018, 10(1): 89. (SCI impact factor: 2.935)

  32. Wang, X.; Young, D. J.; Wu, Y.-L.*; Loh, X. J.* ²Thermogelling 3D Systems towards Stem Cell-Based Tissue Regeneration Therapies.²Molecules, 2018, 23(3): 553. (SCI impact factor: 3.098)

  33. Cai, P.; Zhang, X.; Wang, M.; Wu, Y.-L.; Chen, X.* ²Combinatorial Nano−Bio Interfaces.² ACS Nano, 2018, 12(6): 5078-5084. (SCI impact factor: 13.709)

  34. Wojnilowicz, M.; Besford, Q. A.; Wu, Y.-L.; Loh, X. J.; Braunger, J. A.; Glab, A.; Cortez-Jugo, C.; Caruso, F.*; Cavalieria, F.* ²Glycogen-Nucleic Acid Constructs for Gene Silencing in Multicellular Tumor Spheroids.² Biomaterials, 2018, 176: 34-49. (SCI impact factor: 8.806)

  35. Shan, W.; Zhang, D.; Wu , Y.-L.; Lv, X.; Hu, B.; Zhou, X.; Ye, S.; Bi, S.; Ren, L.*; Zhang, X.* ²Modularized Peptides Modified HBc Virus-Like Particles for Encapsulation and Tumor-Targeted Delivery of Doxorubicin.² Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(3): 725-734. (SCI impact factor: 6.500)

  36. Cai, P.; Hu, B.; Leow, W. R.; Wang, X.; Loh, X. J.; Wu, Y.-L.; Chen, X.* ²Biomechano-Interactive Materials and Interfaces.² Advanced Materials, 2018, 30(31): 1800572. (SCI impact factor: 21.950)

  37. Hu, B.; Owh, C.; Chee, P. L.; Leow, W. R.; Liu, X.; Wu, Y.-L.; Guo, P.; Loh, X. J.*; Chen X.* ²Supramolecular Hydrogels for Antimicrobial Therapy.² Chemical Society Reviews, 2018, 47(18): 6917-6929. (SCI impact factor: 40.182)

  38. Wu, Y.-L.; Engl, W.; Hu, B.; Cai, P.; Leow, W. R.; Tan, N. S.; Lim, C. T.; Chen, X.* ²Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy.²ACS Nano, 2017, 11(7): 6996-7005. (SCI impact factor: 13.942)

  39. Cai, P.; Leow, W. R.; Wang, X.; Wu, Y.-L.*; Chen, X.* ²Programmable Nano-Bio Interfaces for Functional Biointegrated Devices.²Advanced Materials, 2017, 29(26): 1605529. [Featured as Inside Back Cover] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/05/24998/] (SCI impact factor: 19.791)

  40. Liu, X.; Chen, X.; Chua, M. X.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.*²Injectable Supramolecular Hydrogels as Delivery Agents of Bcl-2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors.²Advanced Healthcare Materials, 2017, 6(11): 1700159. [Featured as Front Cover] [Highlighted by Advanced ScienceNews: http://www.advancedsciencenews.com/cover-art-featuring-cancer-therapy-angiogenesis-tissue-engineering/] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/07/25828/] (SCI impact factor: 5.110)

  41. Wang, X.;  Liow, S. S.; Wu, Q.; Li, C.; Owh, C.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.* ²Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy.²Macromolecular Bioscience, 2017, 17(11): 1700186. (SCI impact factor: 3.238)

  42. Li, Z.*; Liu, X.; Chen, X.; Chua, M. X.; Wu, Y.-L.*²Targeted Delivery of Bcl-2 Conversion Gene by MPEG-PCL-PEI-FA Cationic Copolymer to Combat Therapeutic Resistant Cancer.²Materials Science and Engineering: C, 2017, 76: 66-72. (SCI impact factor: 4.164)

  43. Yang, D.-P.; Liu, X.; Teng, C. P.; Owh, C.; Win, K. Y.; Lin, M.; Loh, X. J.; Wu, Y.-L.*; Li, Z.; Ye, E.* ²Unexpected Formation of Gold Nanoflowers by a Green Synthesis Method as Agents for a Safe and Effective Photothermal Therapy.²Nanoscale, 2017, 9(41): 15753–15759. (SCI impact factor: 7.367)

  44. Liow, S. S.; Dou, Q.; Kai, D.; Sugiarto S.; Yu, C. Y. Y.; Kwok, R. T. K.; Chen, X.; Wu, Y.-L.*; Ong, S. T.; Kizhakeyil, A.; Verma N. K.; Tang, B. Z.; Loh, X. J.* ²Long-term Real-time in vivo Drug Release Monitoring with AIE Thermogelling Polymer.²Small, 2017, 13(7): 1603404. [Featured as Back Cover] (SCI impact factor: 8.643)

  45. Zheng, C.; Gao, H.; Yang, D.-P.*; Liu, M.; Cheng, H.; Wu, Y.-L.*; Loh, X. J.* ²PCL-based Thermo-gelling Polymers for In Vivo Delivery of Chemotherapeutics to Tumors.²Materials Science and Engineering: C, 2017, 74: 110-116. (SCI impact factor: 4.164)

  46. Fan, X.; Wang, X.; Cao, M.; Wang, C.; Hu, Z.; Wu, Y.-L.*;Li, Z.*; Loh, X. J.²²Y²-Shape Armed Amphiphilic Star-like Copolymer: Design, Synthesis and Dual-Responsive Unimolecular Micelle Formation for Controlled Drug Delivery.²Polymer Chemistry, 2017, 8(36): 5611-5620. (SCI impact factor: 5.375)

  47. Hu, B.; Leow, W. R.; Cai, P.; Li, Y.-Q.; Wu, Y.-L.; Chen, X.* ²Nanomechanical Force Mapping of Restricted Cell-To-Cell Collisions Oscillating between Contraction and Relaxation.² ACS Nano, 2017, 11(12): 12302-12310. (SCI impact factor: 13.709)

  48. Wang, P.; Zeng, W.; Liu, J.; Wu, Y.-L.; Ma, Y.; Zeng, Z.; Pang, J.-y.*; Zhang, X.-k.; Yan, X.; Wong, A.; Zeng, J.-Z.* ²TRC4, an Improved Triptolide Derivative, Specifically Targets to Truncated Form of Retinoid X Receptor-alpha in Cancer Cells.²Biochemical Pharmacology, 2017, 124: 19-28. (SCI impact factor: 4.581)

  49. Li, J.-F.; Yan, X.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.*²Comprehensive Two-dimensional Normal-phase Liquid Chromatography × Reversed-phase Liquid Chromatography for Analysis of Toad Skin.²Analytica Chimica Acta, 2017, 962: 114-120. (SCI impact factor: 4.950)

  50. Zeng W.; Zhang, C.; Cheng, H.; Wu, Y.-L.; Liu, J.; Chen, Z.; Huang, J. G.; Ericksen, R. E.; Chen, L.; Zhang, H.; Wong, A. S.*; Zhang, X.-k.; Han, W.; Zeng, J.-Z.* ²Targeting to the Non-genomic Activity of Retinoic Acid Receptor-Gamma by Acacetin in Hepatocellular Carcinoma.²Scientific Reports, 2017, 7: 348. (SCI impact factor: 4.259).

  51. Hu, B.; Leow, W. R.; Amini, S.;  Nai, B.; Zhang, X.; Liu, Z.; Cai, P.; Li, Z.; Wu, Y.-L.; Miserez, A.; Lim, C. T.; Chen, X.*²Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re-Epithelialization.²Advanced Materials, 2017, 29(29): 1700145. (SCI impact factor: 19.791)

  52. Wee, C. Y.; Liow, S. S.; Li, Z.; Wu, Y.-L.; Loh, X. J.* ²New Poly[(R)-3-hydroxybutyrate-co-4-hydroxybutyrate] (P3HB4HB)-Based Thermogels.²Macromolecular Chemistry and Physics, 2017, 218(17): 1700196. (SCI impact factor: 2.500)

  53. Wang, Y.-Q.; Tang, X.; Li, J.-F.; Wu, Y.-L.; Sun, Y.-Y.; Fang, M.-J.; Wu, Z.; Wang, X.-M.*; Qiu, Y.-K.*²Development of an On-Line Mixed-Mode Gel Liquid Chromatography × Reversed Phase Liquid Chromatography Method for Separation of Water Extract from Flos Carthami.²Journal of Chromatography A, 2017, 1519: 145-151. (SCI impact factor: 3.981)

  54. Chen, X.; Qiu, Y.-K.; Owh, C.; Loh, X. J.*; Wu, Y.-L.*²Supramolecular Cyclodextrin Nanocarriers for Chemo- and Gene Therapy towards the Effective Treatment of Drug Resistant Cancers.²Nanoscale, 2016, 8(45): 18876-18881. (SCI impact factor: 7.367)

  55. Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Liow, S. S; Li, Z.; Loh, X. J.* ²PHB-based Gels as Delivery Agents of Chemotherapeutics for the Effective Shrinkage of Tumors.²Advanced Healthcare Materials, 2016, 5(20): 2679-2685. [Highlighted by http://www.advancedsciencenews.com/injectable-hydrogels-for-precise-chemotherapy/] (SCI impact factor: 5.110)

  56. Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Loh, X. J.* ²PLA-based Thermogel for the Sustained Delivery of Chemotherapeutics in a Mouse Model of Hepatocellular Carcinoma.²RSC Advances, 2016, 6(50): 44506-44513. (SCI impact factor: 3.108)

  57. Li, J.-F.; Fang, H.; Yan, X.; Chang, F.-R.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.*²On-line Comprehensive Two-dimensional Normal-phase Liquid Chromatography × Reversed-phase Liquid Chromatography for Preparative Isolation of Toad Venom.²Journal of Chromatography A, 2016, 14556(22): 169-175. (SCI impact factor: 3.981)

  58. Lin, N.; Chen, X.; Yan, S.; Wang, H.; Lu, Z.; Xia, X.; Liang, M.; Wu, Y.-L.*; Zheng, L.*; Cao Q.*; Ding, Z. ²An Aggregation-Induced Emission Based pH-sensitive Fluorescent Probe for Intracellular Acidity Sensing.²RSC Advances, 2016, 6(30): 25416-25419. (SCI impact factor: 3.108)

  59. Wu, Y.-L.; Chen, X.; Wang, W.; Loh, X. J.* ²Engineering Bioresponsive Hydrogels towards Healthcare Applications.²Macromolecular Chemistry and Physics, 2016, 217(2): 175-188. [Featured in Front Cover] (SCI impact factor: 2.500)

  60. Cai, P.; Layani, M.; Leow, W. R.; Amini, S.; Liu, Z.; Qi, D.; Hu, B.; Wu, Y.-L.; Miserez, A.; Magdassi, S.; Chen, X.* ²Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration.²Advanced Materials, 2016, 28(16): 3102-3110. (SCI impact factor: 19.791)

  61. Yan, X.; Wang, L.-J.; Wu, Z.; Wu, Y.-L.; Liu, X.-X.; Chang, F.-R.; Fang, M.-J.*; Qiu, Y.-K.* ²New On-Line Separation Workflow of Microbial Metabolites via Hyphenation of Analytical and Preparative Comprehensive Two-Dimensional Liquid Chromatography.²Journal of Chromatography B, 2016, 1033-1034: 1-8. (SCI impact factor: 2.603)

  62. Tay, C. Y.*; Wu, Y.-L.; Cai, P.; Tan, N. S.; Venkatraman, S. S.; Chen, X.; Tan, L. P.* ²Bio-inspired Micropatterned Hydrogel to Direct and Deconstruct Hierarchical Processing of Geometry-force Signals by Human Mesenchymal Stem Cells during Smooth Muscle Cell Differentiation.² NPG Asia Materials, 2015, 7(7): e199. (SCI impact factor: 9.157)

  63. Chen, W.-B.; Li, S.-Q.; Chen, L.-J.; Fang, M.-J.; Chen, Q.-C.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.* ²Online Polar Two Phase Countercurrent Chromatography × High Performance Liquid Chromatography for Preparative Isolation of Polar Polyphenols from Tea Extract in a Single Step.²Journal of Chromatography B, 2015, 997: 179-186. (SCI impact factor: 2.603)

  64. Loh, X. J.*; Wu, Y.-L.²Cationic Star Copolymers Based on β-Cyclodextrins for Efficient Gene Delivery to Mouse Embryonic Stem Cell Colonies.²Chemical Communications, 2015, 51(54): 10815-10818. [Featured in Back Cover] (SCI impact factor: 6.319)

  65. Wang, D.; Chen, L.-J.; Liu, J.-L.; Wang, X.-Y.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.* ²On-line Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography System with a Novel Fragmentary Dilution and Turbulent Mixing Interface for Preparation of Coumarins from Cnidium monnieri.²Journal of Chromatography A, 2015, 1406: 215-223. (SCI impact factor: 3.981)

  66. Hu, B.; Shi, W.; Wu, Y.-L.; Leow, W. R.; Cai, P.; Li, S.; Chen, X.* ²Orthogonally Engineering Matrix Topography and Rigidity to Regulate Multicellular Morphology.² Advanced Materials, 2014, 26(33): 5786-5793. (SCI impact factor: 19.791)

  67. Yin, S.; Wu, Y.-L.; Hu, B.; Wang, Y.; Cai, P.; Tan, C. K.; Qi, D.; Zheng, L.; Leow, W. R.; Tan, N. S.; Wang, S.; Chen, X.* ²Three-dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells.²Advanced Materials Interfaces,2014, 1(1): 1300043. (SCI impact factor: 4.279)

  68. Liu, J.-L.; Wang, X.-Y.; Zhang, L.-L.; Fang, M.-J.; Wu, Y.-L.; Wu, Z.; Qiu, Y.-K.* ²Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography with Heart-cutting and Stop-and-go Techniques for Preparative Isolation of Coumarin Derivatives from Peucedanum praeruptorum Dunn.²Journal of Chromatography A, 2014, 1374 : 156–163. (SCI impact factor: 3.981)

  69. Wu, Y.-L.; Putcha, N.; Ng, K.W.; Leong, D.; Lim, C.T.; Loo, S.C.; Chen, X.* ²Biophysical Responses upon the Interaction of Nanomaterials with Cellular Interfaces.²Accounts of Chemical Research, 2013, 46(3):782-791. (SCI impact factor: 20.268)

  70. Wu, Y.-L.; Yin, H.; Zhao, F.; Li, J.* ²Multifunctional Hybrid Nanocarriers Consisting of Supramolecular Polymers and Quantum Dots for Simultaneous Dual Therapeutics Delivery and Cellular Imaging.²Advanced Healthcare Materials, 2013, 2(2): 297-301. (SCI impact factor: 5.110)

  71. Lam, C.R.; Tan, C.; Teo, Z.; Tay, C.Y.; Phua, T.; Wu, Y.-L.; Cai, P.Q.; Tan, L.P.; Chen, X.; Zhu, P.; Tan, N.S.* ²Loss of TAK1 Increases Cell Traction Force in a ROS-dependent Manner to Drive Epithelial-Mesenchymal Transition of Cancer Cells. ²Cell Death & Disease, 2013, 4: e848. (SCI impact factor: 5.965)

  72. Cai, L.L.; Ye, H.M.; Lv, X.N.; Wu, Y.-L.; Zhang, H.J.; Zheng, L.M.; Tzeng, C.M.* ²25-(OH)VitD3, as a Risk Indicator in Diagnosis of Adenocarcinoma.²Current Drug Targets, 2013, 14(11): 1367-1376. (SCI impact factor: 3.236)

  73. Wu, D.-C.*; Loh, X.J.; Wu, Y.-L.; Lay, C.L.; Liu, Y.*²’Living’ Controlled in situ Gelling Systems: Thiol-Disulfide Exchange Method toward Tailor-Made Biodegradable Hydrogels.²Journal of the American Chemical Society, 2010, 132(43): 15140-1514. (SCI impact factor: 13.858)

  74. Loh, X.J.*; Zhang, Z.-X.; Mya, K.Y.; Wu, Y.-L.; He, C.B.; Li, J.*²Efficient Gene Delivery with Paclitaxel-Loaded DNA-Hybrid Polyplexes Based on Cationic Polyhedral Oligomeric Silsesquioxanes.²Journal of Materials Chemistry, 2010, 20(47): 10634-10642. (SCI impact factor: 6.101)

  75. Wu, Y.-L.; Li, J.*²Synthesis of Supramolecular Nanocapsules Based on Threading Multiple Cyclodextrins over Polymer on Gold Nanoparticles.²Angewandte Chemie International Edition, 2009, 48(21): 3842-3845. [Highlighted by Nature Asia-Pacific: http://www.nature.com/am/journal/2009/200908/full/am2009185a.html] (SCI impact factor: 11.994)

  76. Loh, X.J.; Zhang, Z.-X.; Wu, Y.-L.; Lee, T.S.; Li, J.*²Synthesis of Novel Biodegradable Thermoresponsive Triblock Copolymers Based on Poly[(R)-3-hydroxybutyrate] and Poly(N-isopropylacrylamide) and Their Formation of Thermoresponsive Micelles.²Macromolecules, 2009, 42(1): 194-202. (SCI impact factor: 5.835)

  77. Loh, X.J.; Wu, Y.-L.; Seow, W.T.J.; Norimzan, M.N.I.; Zhang, Z.-X.; Xu, F.-J.; Kang, E.-T.; Neoh, K.-G.; Li, J.*²Micellization and Phase Transition Behavior of Thermosensitive Poly(N-isopropylacrylamide)–Poly(e-caprolactone)–Poly(N-isopropylacrylamide) Triblock Copolymers.²Polymer, 2008, 49(23): 5084-5094. (SCI impact factor: 3.684)

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